OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.
Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.
Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.
Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Archiving: full-text archived in CLOCKSS.
Rapid publication: manuscripts are undertaken in 8 days from acceptance to publication (median values for papers published in this journal in 2020, 1-2 days of FREE language polishing time is also included in this period).
Oxidative Stress and Aging
Submission Deadline: October 15, 2021 (Open) Submit Now
Yu-Chiang Hung, MD, PhD
Professor, Director, Department of Chinese Medicine, College of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, Kaohsiung, Taiwan
Research Interests: Oxidative stress; aging; Chinese medicine; Chinese herbs; acupuncture of complementary and alternative medicine
About This Topic
Aging is a progressive physiological and biological decline of organ function that is accompanied with the development of age-related diseases. As the population ages severely in the world, age-related research has become important issue. However, the causes and mechanisms of aging remain unknown. Oxidative stress increasing amounts of reactive oxygen species may be an important contributor to aging. Gerontology is the study of the aging process and age-related diseases. OBM Geriatrics wants to pick a special topic of "Oxidative Stress and Aging" to publish. We try to answer the following questions:
1. Does oxidative stress and free radicals cause aging?
2. How does oxidative stress and free radicals cause aging?
3. What age-related diseases are associated with oxidative stress and free radicals?
4. What environmental, nutritional and pharmacological strategies are good for decreasing oxidative stress?
OBM Geriatrics would appreciate receiving any manuscript submission about "Oxidative Stress and Aging".
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